科学家
突破性的发现2013 graduate using artificial intelligence and automation to accelerate the discovery and development of life-saving peptide therapeutics for serious illnesses, 包括癌症.
科学家
突破性的发现2013 graduate using artificial intelligence and automation to accelerate the discovery and development of life-saving peptide therapeutics for serious illnesses, 包括癌症.

戴尔·托马斯10岁的时候,卧室里就挂着地图. What fascinated him was how maps were made based on what was known at the time, 以及后来的发现如何改变了这些地图. 如果他有张能预测自己未来的地图, 展示了他从家乡汉普顿出发的旅程, 缅因州, 到船的桥, to the scientific exploration of the deep chemical contours of human biology and the study of peptides.

戴尔·托马斯。

戴尔·托马斯的13
共同创办Mytide疗法

托马斯的13位合伙人共同创立了Mytide Therapeutics, a company that uses artificial intelligence and automation to shorten the time required to make peptides, 在医学研究和治疗中有价值的. One of the promises of Mytide’s platform is that a researcher may be able to “order” a peptide for a specific single patient that will be part of his or her cancer therapy. 根据托马斯, the company is working to enable peptides to be a low cost personalized therapeutic in the not too distant future.

Peptides are building blocks that carry signals in cells and throughout the body. 传统上,它们的生产既昂贵又耗时, 用传统方法在实验室里制作需要六周时间. Thomas and a team of co-workers set a goal to be able to produce peptides in closer to 23 hours.

当人类患上癌症或其他疾病时, 某些关键故障可能发生在单个细胞内部. A peptide is the right size to enter a cell and can carry other material with it, such as a therapy. Advances in design and molecular 工程 have made these therapeutics a practical solution for curing complex diseases. 事实上, some vaccines against COVID-19 were designed to allow a tiny container of fat to carry a messenger RNA to help spur the immune response.

“I am always looking for opportunity to positively impact peoples’ lives. 我相信无论你是在移动一艘船还是在制造药物, 它们提出了一系列类似的问题.”

In the biotechnology world, the market for peptides was estimated at $28.4 billion in the United States in 2020 when excluding insulin, by one analysis at Yahoo Finance. 生物积木, 像肽, are seeing a resurgence in the biotechnology industry as companies look to cure increasingly difficult to treat illnesses faster while taking a more personalized approach.

非传统的思想家

作为独生子, 托马斯生长在一个重视教育的家庭, and he recalls his ambitions eventually included studying science and 工程 in graduate school. 他就读于汉普顿学院,在那里他很喜欢学术, and he recognized M8体育APP (MMA) would be a great place to study 工程.

在综合格斗比赛中,他学会了成为一名领导者. One of Thomas’ 工程 professors described him as having “diligent preparation, 非常规思维, 和纯粹的坚韧.” Thomas distinguished himself by completing the 5-year systems 工程 degree in four years and was named the Class of 2013 valedictorian as well as a Scheel Scholar.

肽构建块

“I was thinking of going into the shipping industry or working for Georgia Pacific at a paper plant, 然后在我高三的时候, 我申请了斯坦福大学, 哥伦比亚, 麻省理工学院(MIT),”他回忆道. 他被麻省理工学院录取了, 选择制造工程的研究生课程, 继续攻读博士学位.D. in mechanical 工程 where he obtained a perfect grade point average.

为他, 麻省理工学院将为广泛的科学提供一个肥沃的地方, 工程, 和创业.

“我能够完善自己独特的系统级别方法, and really saw how the confluence of my experiences could solve decades old problems within the manufacture molecules (such as peptides),”他说. 他称之为“偶然循环”.”

Some of his interest in leadership may have come from early summers with his grandfather in Brooks, 缅因州.

“I got to work alongside him and watch him think like an owner … from that inspiration I did want to start my own company at some point. Given that background, I took advantage of studying entrepreneurship at MIT,”他说.

在事后看来, as Thomas looks back on the map drawn by his actual steps along his career, 他对自己的选择很满意.

“I am always looking for opportunity to positively impact peoples’ lives. 我相信无论你是在移动一艘船还是在制造药物, 它们提出了一系列类似的问题. I have been fortunate throughout my career to be enabled to explore my full intellectual curiosity and work towards driving impact across industries.

MMA ABS的建筑

Thanks to an ABS Fellowship, Thomas was able to finish his graduate work at MIT. MMA的ABS工程中心, 科学, and Research provides state-of-the-art teaching and research laboratories, 教室, 研究空间, and more at the center of the campus to inspire future engineers and scientists.

“船是一座漂浮的城市. That city has electricity, it has propulsion, and it has refrigeration. 缅因州 Maritime really helped me focus on complex systems,” said Thomas.

如今,他在波士顿生活和工作. He says steering a city-sized ship with complex systems and a team of experts is not that different from steering a company making complex molecules.

When asked if he has any hobbies, Thomas chuckles and says that his company is his hobby.

“我仍在研究工作与生活的平衡公式.”

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